Rare Infectious Disease News

Advertisement

Disease Profile

Actinic lichen planus

Prevalence
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.

Unknown

US Estimated

Europe Estimated

Age of onset

All ages

ageofonset-all.svg

ICD-10

L43.8

Inheritance

Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.

no.svg

Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.

no.svg

X-linked
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.

no.svg

X-linked
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.

no.svg

Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.

no.svg

Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.

no.svg

Not applicable

no.svg

Other names (AKA)

Actinic LP; Lichen planus actinus; Lichen planus subtropicus;

Categories

Skin Diseases

Summary

Actinic lichen planus (LP) is a rare form of lichen planus, which is a condition that affects the skin and/or mouth. In actinic LP, specifically, affected people develop mildly itchy, coin-shaped patches on sun exposed areas such as the face, the neck and the backs of the hands.[1][2] It is extremely rare in Caucasians but it is more common in dark-skinned populations. The exact underlying cause of actinic LP is unknown.[3] Treatment is not always necessary as some cases of actinic LP resolve on their own. Mild cases can often be managed with topical steroids, while more intensive therapies may be required for severe cases.[1][2]

Learn more

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

Where to Start

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.

In-Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Actinic lichen planus. Click on the link to view a sample search on this topic.

References

  1. Lichen planus. DermNet NZ. March 2015; https://dermnetnz.org/scaly/lichen-planus.html.
  2. Tsu-Yi Chuang, MD, MPH. Lichen Planus. Medscape Reference. May 2015; https://emedicine.medscape.com/article/1123213-overview.
  3. Actinic lichen planus. Orphanet. May 2011; https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=254395.