Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.
Age of Onset
Autosomal dominant ?A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease
Autosomal recessive ?Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype
X-linked dominant ?X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
X-linked recessive ?Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder
Mitochondrial or multigenic ?Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.
Multigenic or multifactor ?Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.
C1q nephropathy is a
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
- C1q Nephropathy. Division of Nephrology and Hypertension. UNC Kidney Center. https://unckidneycenter.org/kidneyhealthlibrary/glomerular-disease/c1q-nephropathy.
- Meyrier A & Apperl GB. Minimal change variants: Mesangial proliferation; IgM nephropathy; C1q nephropathy. UpToDate. January 13, 2016; https://www.uptodate.com/contents/minimal-change-variants-mesangial-proliferation-igm-nephropathy-c1q-nephropathy.
- Devasahayam J & cols. C1q Nephropathy: The Unique Underrecognized Pathological Entity. Anal Cell Pathol (Amst).. November 10, 2015; 2015 (490413):https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657067/.