Rare Infectious Disease News

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Recurrent respiratory papillomatosis (RRP)

Recurrent respiratory papillomatosis (RRP) is a rare viral disease where tumors (papillomas) grow in the respiratory tract)

Prevalence

1-9 / 100,000

3,310 - 29,790

US Estimated

1-9 / 100,000

5,135 - 46,215

Europe Estimated

Age of Onset

ageofonset-childhood.svg

ICD-10

-

Inheritance

Autosomal dominant

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Autosomal recessive

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Mitochondrial/Multigenic

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X-linked dominant

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X-linked recessive

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5 Facts you should know

FACT

1

The tumors are caused by human papillomavirus (HPV) infection of the throat.

FACT

2

The tumors may lead to narrowing of the airway, which may cause vocal changes or airway obstruction.

FACT

3

There are two types of RRP - juvenile-onset and adult-onset.

FACT

4

They may vary in size and grow very quickly, and may grow back even when removed.

FACT

5

These tumors rarely become cancerous, but can cause long-term airway and voice complications.

Recurrent respiratory papillomatosis (RRP)

Recurrent respiratory papillomatosis

RRP; Juvenile laryngeal papilloma; Laryngeal papilloma, recurrent; Juvenile-onset recurrent respiratory papillomatosis (type); JORRP (type); Adult-onset recurrent respiratory papillomatosis (type); AORRP

What’s your rare IQ?

Recurrent respiratory papillomatosis is caused by which two HPV viruses?

Common Signs & Symptoms

Dysphonia

Voice hoarseness

Benign tumors in the airway

(non-cancerous)

Dyspnea

Shortness of breath

Chronic cough

Respiratory distress

Breathing difficulties
Difficulty breathing

Increased proportion of transitional B cells

Failure to thrive

Faltering weight
Weight faltering

Hemoptysis

Coughing up blood

Top clinical studies

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Top treatments in development

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